An account of the blues experience through the recollections and performances of B.B. King, Son Thomas, inmates from Parchman prison, a barber from Clarkesdale, a salesman from Beale Street, and others.

Give My Poor Heart Ease is one of a series of films made in Mississippi in the mid 1970s by William Ferris and the Center for Southern Folklore and produced in association with Howard Sayre Weaver.